Search results for " platform"
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Platform Technologies Improve Protein Expression
In addition to exploring novel production methods such as continuous processes and disposable production technology, manufacturers also heavily invest in platform technologies for protein expression t…
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Evolution of the Monoclonal Antibody Purification Platform
What is unique about mAbs from a processing perspective is the applicability of developing a common process and analytical platform (2, 3). Some process development related attributes with respect to …
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The Development and Application of a Monoclonal Antibody Purification Platform
The following article describes the development of a purification platform for monoclonal antibodies (MAbs) at Pfizer's Global Biologics division, including how the individual unit operations have bee…
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Platform Approach Speeds Process Development
Chinese hamster ovary (CHO)-based cell culture platforms should combine state-of the-art technologies for genetic vectors, host cell portfolio, cell line generation, cultivation media, and process des…
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A Platform Approach for the Identity Testing of Multi-Component Cell-Culture Media
As part of this approach, a platform glucose method that utilizes a linear standard curve was validated using alternative cell-culture media, and all established acceptance criteria were met. The assa…
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Genetic Vaccine Platforms Demonstrate Their Potential
Development and manufacturing advantages for genetic vaccines
What makes genetic vaccines so attractive is the potential to establish platform solutions that allow the r…
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Combining Microbioreactors and Advanced Statistical Techniques to Optimize a Platform Process for a New Host-Cell Line
Example of a process optimization
The aforementioned approach to process optimization can be illustrated with an example (using artificial data) of the optimization of an existing platform…
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Modular Manufacturing Platforms for Biologics
…dule/Morimatsu); or building modules with process systems (such as Cytiva’s KUBio FlexFactory platform). According to Pär Almhem, president of ModWave, modular design and construction in pharmaceutic…
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A Platform Approach to Purification of Antibody Fragments
However, due to their high molecular diversity, the use of a purification platform approach (i.e., standard sets of unit operations, conditions, and methods applied to a given class of molecules) is m…
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A Platform Approach for the Purification of Domain Antibodies (Dabs)
This platform approach, based on a capture step with Capto L, enables increased efficiency and productivity in developing therapeutics based on Dabs.
Click here to download the application not…